Symbol Name ID |
Gabbr1
gamma-aminobutyric acid type B receptor subunit 1 MGI:1860139 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Addictive alcohol use |
Disease(s) Associated with GABBR1 | |
alcohol dependence |
Mouse Phenotypes | nervous system phenotype |
seizures |
audiogenic seizures |
clonic seizures |
tonic-clonic seizures |
absence seizures |
sporadic seizures |
abnormal axon morphology |
abnormal myelin sheath morphology |
abnormal somatic nervous system morphology |
abnormal lumbar dorsal root ganglion morphology |
abnormal sciatic nerve morphology |
abnormal myelination |
abnormal nervous system electrophysiology |
abnormal action potential |
abnormal neuron physiology |
abnormal synaptic transmission |
abnormal CNS synaptic transmission |
abnormal excitatory postsynaptic currents |
abnormal inhibitory postsynaptic currents |
abnormal inhibitory postsynaptic potential |
reduced long-term potentiation |
increased prepulse inhibition |
|
Availability | Mouse Genotype | |||||||||||||||||||||||
Gabbr1tm1Bet/Gabbr1tm1Bet | ||||||||||||||||||||||||
Gabbr1tm1Pngl/Gabbr1tm1Pngl | * | |||||||||||||||||||||||
Gabbr1tm3Bet/Gabbr1tm3Bet | ||||||||||||||||||||||||
Gabbr1tm4Bet/Gabbr1tm4Bet | ||||||||||||||||||||||||
Gabbr1tm1Pngl/Gabbr1+ | ||||||||||||||||||||||||
Gabbr1tm2Bet/Gabbr1tm2Bet Tg(HCRT-cre)1Stak/0 (conditional) |
* | |||||||||||||||||||||||
Gabbr1tm2Bet/Gabbr1tm2Bet Hdctm1.1(icre)Wwis/Hdc+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 08/02/2024 MGI 6.24 |
|
|