Symbol Name ID |
Ncstn
nicastrin MGI:1891700 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | EEG abnormality |
Delusion |
Schizophrenia |
Hallucinations |
Negativism |
Social and occupational deterioration |
Disease(s) Associated with NCSTN | ||||||
schizophrenia |
Mouse Phenotypes | nervous system phenotype |
increased neuron apoptosis |
increased embryonic neuroepithelium apoptosis |
abnormal neural tube morphology |
abnormal neural crest morphology |
kinked neural tube |
loss of cortex neurons |
thin cerebral cortex |
astrocytosis |
gliosis |
decreased CNS synapse formation |
decreased myelin sheath thickness |
abnormal dendrite morphology |
dysmyelination |
decreased prepulse inhibition |
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Availability | Mouse Genotype | |||||||||||||||
Ncstntm1Pcw/Ncstntm1Pcw | ||||||||||||||||
Ncstntm1Rroz/Ncstntm1Rroz | ||||||||||||||||
Ncstntm1.1Sud/Ncstntm1.1Sud Tg(Camk2a-cre)1Shn/0 (conditional) |
* | |||||||||||||||
Ncstntm1.1Sud/Ncstntm1.1Sud Olig1tm1(cre)Rth/Olig1+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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