Symbol Name ID |
Prickle1
prickle planar cell polarity protein 1 MGI:1916034 |
Darker colors indicate more annotations |
Human Phenotypes | Sensory axonal neuropathy |
Ataxia |
Dysmetria |
Myoclonus |
Tremor |
Babinski sign |
Dysarthria |
Generalized myoclonic seizure |
Atonic seizure |
Disease(s) Associated with PRICKLE1 | |||||||||
progressive myoclonus epilepsy 1B |
Mouse Phenotypes | increased susceptibility to pharmacologically induced seizures |
abnormal seizure response to electrical stimulation |
delayed neural tube closure |
abnormal cochlear hair cell stereociliary bundle morphology |
short cochlear hair cell stereocilia |
enlarged lateral ventricles |
abnormal striatum morphology |
abnormal hippocampus morphology |
abnormal innervation |
abnormal nervous system tract morphology |
abnormal excitatory synapse morphology |
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Availability | Mouse Genotype | |||||||||||
Prickle1em1Yzou/Prickle1em1Yzou | ||||||||||||
Prickle1tm1.2Asw/Prickle1tm1.2Asw | ||||||||||||
Prickle1em1Yzou/Prickle1+ | ||||||||||||
Prickle1m1Ingm/Prickle1+ | ||||||||||||
Prickle1m2Ingm/Prickle1+ | ||||||||||||
Prickle1tm1Nue/Prickle1+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 06/12/2024 MGI 6.13 |
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