Symbol
Name
ID

Dnm1l
dynamin 1-like
MGI:1921256

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Mouse Phenotypes

abnormal Purkinje cell mitochondrial morphology

increased neuron apoptosis

increased brain apoptosis

decreased embryonic neuroepithelium thickness

abnormal brain morphology

abnormal cerebellum development

reduced cerebellar foliation

forebrain hypoplasia

enlarged brain ventricles

abnormal brain white matter morphology

abnormal brainstem morphology

abnormal cerebellar Purkinje cell layer

decreased Purkinje cell number

small cerebellum

abnormal subarachnoid space morphology

decreased CNS synapse formation

abnormal neurite morphology

abnormal dendritic spine morphology

abnormal synapse morphology

abnormal optic disk morphology

enhanced sensorimotor gating

increased prepulse inhibition

Availability

Mouse Genotype

Dnm1l^em1Hise/Dnm1l^em1Hise

Dnm1l^em1Hise/Dnm1l^em1Hise
Tg(Thy1-EGFP)MJrs/0

Dnm1l^tm1.2Miha/Dnm1l^tm1.2Miha

Dnm1l^{tm1b(KOMP)Wtsi}/Dnm1l⁺

Dnm1l^tm1.1Hise/Dnm1l^tm1.1Hise
En1^tm2(cre)Wrst/En1⁺ (conditional)

Dnm1l^tm1.1Miha/Dnm1l^tm1.1Miha
Tg(Nes-cre)1Kln/0 (conditional)

Dnm1l^tm1.1Hise/Dnm1l^tm1.2Hise
En1^tm2(cre)Wrst/En1⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 07/02/2024 MGI 6.13