Symbol Name ID |
Tdo2
tryptophan 2,3-dioxygenase MGI:1928486 |
Darker colors indicate more annotations |
Human Phenotypes | Echolalia |
Phonic tics |
Depression |
Emotional lability |
Amplification of sexual behavior |
Aggressive behavior |
Attention deficit hyperactivity disorder |
Stuttering |
Compulsive behaviors |
Motor tics |
Self-mutilation |
Intellectual disability |
Intellectual disability, moderate |
Sleep abnormality |
Global developmental delay |
Disease(s) Associated with TDO2 | |||||||||||||||
familial hypertryptophanemia | |||||||||||||||
Gilles de la Tourette syndrome |
Mouse Phenotypes | abnormal neuron differentiation |
abnormal neuronal precursor proliferation |
abnormal olfactory bulb development |
small lateral ventricles |
increased prepulse inhibition |
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Availability | Mouse Genotype | |||||
Tdo2tm1Tnak/Tdo2tm1Tnak | ||||||
Tdo2tm1b(KOMP)Mbp/Tdo2+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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