Symbol Name ID |
Vangl2
VANGL planar cell polarity 2 MGI:2135272 |
* | Aspects of the system are reported to show a normal phenotype. |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Spinal dysraphism |
Disease(s) Associated with VANGL2 | |
neural tube defect |
Mouse Phenotypes | nervous system phenotype |
abnormal neural plate morphology |
abnormal neural tube morphology |
abnormal embryonic neuroepithelium morphology |
enlarged floor plate |
abnormal neural tube closure |
delayed neural tube closure |
open neural tube |
spina bifida |
craniorachischisis |
abnormal cochlear hair cell morphology |
increased cochlear hair cell number |
increased cochlear outer hair cell number |
abnormal orientation of inner hair cell stereociliary bundles |
abnormal orientation of cochlear hair cell stereociliary bundles |
abnormal orientation of outer hair cell stereociliary bundles |
abnormal cochlear inner hair cell morphology |
abnormal cochlear outer hair cell morphology |
abnormal vestibular hair cell morphology |
abnormal brain morphology |
abnormal brain development |
abnormal cervical flexure morphology |
abnormal forebrain development |
abnormal midbrain development |
abnormal brain ventricular system morphology |
abnormal brain ventricle morphology |
enlarged lateral ventricles |
enlarged third ventricle |
abnormal lateral ventricle morphology |
abnormal corpus callosum morphology |
abnormal midbrain morphology |
abnormal forebrain morphology |
abnormal dorsal striatum morphology |
abnormal hippocampus morphology |
abnormal cerebral hemisphere morphology |
abnormal hindbrain morphology |
abnormal metencephalon morphology |
exencephaly |
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Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||
Vangl2em1(IMPC)Mbp/Vangl2em1(IMPC)Mbp | |||||||||||||||||||||||||||||||||||||||
Vangl2Lp-m1Jus/Vangl2Lp-m1Jus | |||||||||||||||||||||||||||||||||||||||
Vangl2Lp/Vangl2Lp | * | ||||||||||||||||||||||||||||||||||||||
Vangl2ska17/Vangl2ska17 | |||||||||||||||||||||||||||||||||||||||
Vangl2tm1.2Mdea/Vangl2tm1.2Mdea | ! | ||||||||||||||||||||||||||||||||||||||
Vangl2tm1.2Yy/Vangl2tm1.2Yy | |||||||||||||||||||||||||||||||||||||||
Vangl2tm2.2Mdea/Vangl2tm2.2Mdea | |||||||||||||||||||||||||||||||||||||||
Vangl2Lp-2J/Vangl2+ | |||||||||||||||||||||||||||||||||||||||
Vangl2Lp/Vangl2+ | *! | ! | |||||||||||||||||||||||||||||||||||||
Vangl2Lp/Vangl2Lp-m1Jus | |||||||||||||||||||||||||||||||||||||||
Vangl2Lp/Vangl2ska17 | |||||||||||||||||||||||||||||||||||||||
Vangl2Lp/Vangl2tm1.2Mdea | |||||||||||||||||||||||||||||||||||||||
Vangl2M1Yzcm/Vangl2+ | |||||||||||||||||||||||||||||||||||||||
Tg(Pax2-cre)1Akg/0 Vangl2tm1.2Mdea/Vangl2tm2.1Mdea (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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