Symbol Name ID |
Nlgn1
neuroligin 1 MGI:2179435 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | EEG abnormality |
Inflexible adherence to routines |
Delayed speech and language development |
Abnormal nonverbal communicative behavior |
Lack of spontaneous play |
Impaired ability to form peer relationships |
Autism |
Motor stereotypy |
Restrictive behavior |
Intellectual disability |
Seizure |
Disease(s) Associated with NLGN1 | |||||||||||
autistic disorder |
Mouse Phenotypes | nervous system phenotype |
abnormal CNS synaptic transmission |
decreased excitatory postsynaptic current amplitude |
|
Availability | Mouse Genotype | |||
Nlgn1em1Taku/Nlgn1em1Taku | * | |||
Nlgn1tm1Bros/Nlgn1tm1Bros | ||||
Nlgn1em1Taku/Nlgn1+ | * | |||
Tg(Thy1-Nlgn1)6Hnes/0 | * | |||
Nlgn1tm1.1Sud/Nlgn1tm1.1Sud Tg(Pcp2-cre)2Mpin/? (conditional) |
* |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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