Symbol Name ID |
Lrp4
low density lipoprotein receptor-related protein 4 MGI:2442252 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Facial palsy |
Cranial nerve compression |
Spastic ataxia |
Tetraparesis |
Hyporeflexia |
Gait disturbance |
Delayed gross motor development |
Disease(s) Associated with LRP4 | |||||||
Cenani-Lenz syndactyly syndrome | |||||||
congenital myasthenic syndrome 17 | |||||||
sclerosteosis 2 |
Mouse Phenotypes | nervous system phenotype |
abnormal motor neuron morphology |
abnormal neuromuscular synapse morphology |
failure of neuromuscular synapse postsynaptic differentiation |
failure of neuromuscular synapse presynaptic differentiation |
abnormal phrenic nerve morphology |
abnormal endplate potential |
abnormal miniature endplate potential |
|
Availability | Mouse Genotype | ||||||||
Lrp4mitt/Lrp4mitt | |||||||||
Lrp4mte/Lrp4mte | |||||||||
Lrp4tm1Her/Lrp4tm1Her | |||||||||
Lrp4tm2Her/Lrp4tm2Her | |||||||||
Lrp4tm1.1Line/Lrp4tm1.1Line Tg(ACTA1-cre)79Jme/0 (conditional) |
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Lrp4tm1.1Line/Lrp4tm1.1Line Mnx1tm4(cre)Tmj/Mnx1+ (conditional) |
* | ||||||||
Lrp4tm1.1Line/Lrp4tm1.1Line Mnx1tm4(cre)Tmj/Mnx1+ Tg(ACTA1-cre)79Jme/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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