Symbol Name ID |
Slitrk2
SLIT and NTRK-like family, member 2 MGI:2679449 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Spasticity |
Ventriculomegaly |
Hippocampal atrophy |
Thin corpus callosum |
Corpus callosum atrophy |
Reduced cerebral white matter volume |
Cerebral palsy |
Phonic tics |
Absent speech |
Delayed speech and language development |
Anxiety |
Autistic behavior |
Aggressive behavior |
Compulsive behaviors |
Hyperactivity |
Intellectual disability |
Dystonia |
Unsteady gait |
Global developmental delay |
Seizure |
Disease(s) Associated with SLITRK2 | ||||||||||||||||||||
non-syndromic X-linked intellectual developmental disorder 111 |
Mouse Phenotypes | nervous system phenotype |
abnormal serotonergic neuron morphology |
abnormal synapse morphology |
abnormal postsynaptic density morphology |
abnormal excitatory synapse morphology |
abnormal excitatory postsynaptic potential |
abnormal miniature excitatory postsynaptic currents |
|
Availability | Mouse Genotype | |||||||
Slitrk2tm1.1Jaru/Slitrk2tm1.1Jaru | * | |||||||
Slitrk2tm1.1Jwum/Y Tg(Nes-cre)1Atp/0 (conditional) |
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Slitrk2tm1.1Jwum/Y (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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