Symbol Name ID |
Glra1
glycine receptor, alpha 1 subunit MGI:95747 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Frequent falls |
Exaggerated startle response |
Myoclonus |
Hypokinesia |
Seizure |
Nocturnal seizures |
Disease(s) Associated with GLRA1 | ||||||
hyperekplexia 1 |
Mouse Phenotypes | nervous system phenotype |
increased susceptibility to pharmacologically induced seizures |
seizures |
tonic-clonic seizures |
decreased neuron number |
abnormal nervous system electrophysiology |
abnormal single cell response |
abnormal CNS synaptic transmission |
abnormal inhibitory postsynaptic currents |
abnormal miniature inhibitory postsynaptic currents |
decreased miniature inhibitory postsynaptic current amplitude |
decreased miniature inhibitory postsynaptic current frequency |
abnormal channel response |
|
Availability | Mouse Genotype | |||||||||||||
Glra1m1Cpai/Glra1m1Cpai | ||||||||||||||
Glra1nmf11/Glra1nmf11 | ||||||||||||||
Glra1spd-ot9J/Glra1spd-ot9J | ||||||||||||||
Glra1spd-ot/Glra1spd-ot | * | |||||||||||||
Glra1tm1.1Geh/Glra1tm1.1Geh | ||||||||||||||
Glra1tm1Betz/Glra1tm1Betz | ||||||||||||||
Glra1tm1Rah/Glra1tm1Rah | ||||||||||||||
Glra1tm2.1Geh/Glra1tm2.1Geh | ||||||||||||||
Glra1tm1Rah/Glra1+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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