Symbol Name ID |
Lrp2
low density lipoprotein receptor-related protein 2 MGI:95794 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Aplasia/Hypoplasia of the corpus callosum |
Agenesis of corpus callosum |
Partial agenesis of the corpus callosum |
Intellectual disability |
Global developmental delay |
Seizure |
Disease(s) Associated with LRP2 | ||||||
Donnai-Barrow syndrome |
Mouse Phenotypes | nervous system phenotype |
abnormal embryonic neuroepithelium morphology |
delayed neural tube closure |
abnormal brain morphology |
abnormal forebrain development |
small embryonic telencephalon |
holoprosencephaly |
abnormal lateral ventricle morphology |
abnormal choroid plexus morphology |
choroid plexus hyperplasia |
absent corpus callosum |
abnormal forebrain morphology |
abnormal diencephalon morphology |
abnormal telencephalon morphology |
abnormal cerebral cortex morphology |
abnormal olfactory bulb morphology |
absent olfactory bulb |
small olfactory bulb |
abnormal cerebellum fissure morphology |
exencephaly |
abnormal dendrite morphology |
decreased retina ganglion cell number |
abnormal retina bipolar cell morphology |
abnormal optic nerve morphology |
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Availability | Mouse Genotype | ||||||||||||||||||||||||
Lrp227SH/Lrp227SH | |||||||||||||||||||||||||
Lrp2m267Asp/Lrp2m267Asp Tg(Rr291-lacZ)#Mekk/0 |
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Lrp2m267Asp/Lrp2m267Asp | |||||||||||||||||||||||||
Lrp2tm1Her/Lrp2tm1Her | |||||||||||||||||||||||||
Lrp2tm1Tew/Lrp2tm1Tew | * | ||||||||||||||||||||||||
Foxg1tm1(cre)Skm/Foxg1+ Lrp2tm1Tew/Lrp2tm1Tew (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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