Symbol Name ID |
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1) MGI:95808 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Interictal epileptiform activity |
Absent speech |
Self-injurious behavior |
Intellectual disability, severe |
Sleep abnormality |
Delayed fine motor development |
Seizure |
Disease(s) Associated with GRIA1 | |||||||
autosomal recessive intellectual developmental disorder 76 |
Mouse Phenotypes | nervous system phenotype |
abnormal dendrite morphology |
abnormal spinal cord morphology |
abnormal nervous system electrophysiology |
impaired ability to fire action potentials |
impaired synaptic plasticity |
abnormal excitatory postsynaptic potential |
abnormal glutamate-mediated receptor currents |
reduced AMPA-mediated synaptic currents |
abnormal long-term potentiation |
reduced long-term potentiation |
abnormal miniature excitatory postsynaptic currents |
decreased prepulse inhibition |
absent long-term depression |
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Availability | Mouse Genotype | ||||||||||||||
Gria1em1(IMPC)H/Gria1em1(IMPC)H | |||||||||||||||
Gria1em1(IMPC)Hmgu/Gria1em1(IMPC)Hmgu | |||||||||||||||
Gria1tm1Rlh/Gria1tm1Rlh | |||||||||||||||
Gria1tm1Rsp/Gria1tm1Rsp | * | ||||||||||||||
Gria1tm2Rlh/Gria1tm2Rlh | * | ||||||||||||||
Gria1tm4Rlh/Gria1tm4Rlh | |||||||||||||||
Gria1tm7Rlh/Gria1tm7Rlh | * | ||||||||||||||
Gria1tm2Rsp/Gria1tm2Rsp Tg(Pvalb-cre)1Mony/0 (conditional) |
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Gria1tm2Rsp/Gria1tm2Rsp Tg(Slc6a3-icre)9075Gsc/0 (conditional) |
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Gria1tm2Rsp/Gria1tm2Rsp (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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