Symbol Name ID |
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3) MGI:95810 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Spasticity |
Ventriculomegaly |
Frontal cortical atrophy |
Hypoplasia of the corpus callosum |
Cerebellar vermis hypoplasia |
Retrocerebellar cyst |
Myoclonus |
Limb tremor |
Babinski sign |
Interictal epileptiform activity |
Reduced eye contact |
Delayed speech and language development |
Severe expressive language delay |
Atypical behavior |
Autistic behavior |
Autism |
Aggressive behavior |
Self-injurious behavior |
Self-mutilation |
Intellectual disability |
Intellectual disability, mild |
Intellectual disability, moderate |
Intellectual disability, severe |
Sleep abnormality |
Sleep-wake cycle disturbance |
Hyperreflexia |
Hyporeflexia |
Global developmental delay |
Motor delay |
Specific learning disability |
Seizure |
Bilateral tonic-clonic seizure |
Focal tonic seizure |
Status epilepticus |
Pain insensitivity |
Disease(s) Associated with GRIA3 | |||||||||||||||||||||||||||||||||||
syndromic X-linked intellectual disability 94 |
Mouse Phenotypes | nervous system phenotype |
decreased susceptibility to pharmacologically induced seizures |
abnormal long-term potentiation |
abnormal miniature excitatory postsynaptic currents |
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Availability | Mouse Genotype | ||||
Gria3tm1Rlh/Gria3tm1Rlh | * | ||||
Gria3tm2Rlh/Gria3tm2Rlh | * | ||||
Gria3em1Wthg/Y | |||||
Gria3tm1Dgen/Y | |||||
Gria3tm1Zpj/Y |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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