Symbol Name ID |
Grik2
glutamate receptor, ionotropic, kainate 2 (beta 2) MGI:95815 |
Darker colors indicate more annotations |
Human Phenotypes | Torticollis |
Gliosis |
Cerebellar atrophy |
Neuronal loss in central nervous system |
Gait ataxia |
Bradykinesia |
Chorea |
Involuntary movements |
Myoclonus |
Kinetic tremor |
Postural tremor |
Depression |
Reduced social responsiveness |
Personality changes |
Dementia |
Intellectual disability |
Intellectual disability, mild |
Hyperreflexia |
Global developmental delay |
Seizure |
Atonic seizure |
Disease(s) Associated with GRIK2 | |||||||||||||||||||||
autosomal recessive intellectual developmental disorder 6 | |||||||||||||||||||||
Huntington's disease |
Mouse Phenotypes | decreased susceptibility to pharmacologically induced seizures |
increased susceptibility to pharmacologically induced seizures |
abnormal single cell response |
abnormal CNS synaptic transmission |
abnormal excitatory postsynaptic potential |
abnormal glutamate-mediated receptor currents |
abnormal long-term potentiation |
reduced long-term potentiation |
decreased paired-pulse facilitation |
|
Availability | Mouse Genotype | |||||||||
Grik2tm1Bvis/Grik2tm1Bvis | ||||||||||
Grik2tm1Sfh/Grik2tm1Sfh |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 07/05/2024 MGI 6.24 |
|
|