Symbol
Name
ID

Grin2a
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
MGI:95820

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Gliosis

Cerebellar atrophy

Neuronal loss in central nervous system

Gait ataxia

Bradykinesia

Chorea

EEG abnormality

Depression

Delusion

Schizophrenia

Hallucinations

Negativism

Personality changes

Addictive alcohol use

Dementia

Social and occupational deterioration

Hyperreflexia

Seizure

Disease(s) Associated with GRIN2A

alcohol dependence

Huntington's disease

schizophrenia

Mouse Phenotypes		nervous system phenotype	decreased kindling response	abnormal excitatory postsynaptic currents	reduced NMDA-mediated synaptic currents	reduced long-term potentiation	abnormal miniature excitatory postsynaptic currents
Availability	Mouse Genotype	nervous system phenotype	decreased kindling response	abnormal excitatory postsynaptic currents	reduced NMDA-mediated synaptic currents	reduced long-term potentiation	abnormal miniature excitatory postsynaptic currents
	Grin2a^tm1.1Jpleo/Grin2a^tm1.1Jpleo	*
	Grin2a^tm1.1Ppao/Grin2a^tm1.1Ppao
	Grin2a^tm1.1Tnkw/Grin2a^tm1.1Tnkw	*
	Grin2a^tm1Mim/Grin2a^tm1Mim
	Grin2a^tm1Nak/Grin2a^tm1Nak	*
	Grin2a^tm1Rsp/Grin2a^tm1Rsp	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 08/02/2024 MGI 6.24