Symbol Name ID |
Kcna2
potassium voltage-gated channel, shaker-related subfamily, member 2 MGI:96659 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Ataxia |
Myoclonus |
Tremor |
EEG with spike-wave complexes (2.5-3.5 Hz) |
Absent speech |
Intellectual disability |
Epileptic encephalopathy |
Global developmental delay |
Seizure |
Febrile seizure (within the age range of 3 months to 6 years) |
Myoclonic seizure |
Disease(s) Associated with KCNA2 | |||||||||||
developmental and epileptic encephalopathy 32 |
Mouse Phenotypes | nervous system phenotype |
increased susceptibility to pharmacologically induced seizures |
seizures |
tonic seizures |
abnormal nervous system electrophysiology |
abnormal action potential |
impaired ability to fire action potentials |
abnormal brain wave pattern |
abnormal single cell response |
abnormal inhibitory postsynaptic currents |
abnormal miniature inhibitory postsynaptic currents |
abnormal channel response |
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Availability | Mouse Genotype | ||||||||||||
Kcna2Pgu/Kcna2Pgu | * | ||||||||||||
Kcna2tm1Tem/Kcna2tm1Tem | |||||||||||||
Kcna2Pgu/Kcna2+ | |||||||||||||
Kcna2tm1Tem/Kcna2+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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