Symbol Name ID |
Pax3
paired box 3 MGI:97487 |
* | Aspects of the system are reported to show a normal phenotype. |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Microcephaly |
Aganglionic megacolon |
Spastic paraplegia |
Meningocele |
Myelomeningocele |
Spina bifida |
Intellectual disability |
Delayed fine motor development |
Disease(s) Associated with PAX3 | ||||||||
Waardenburg syndrome | ||||||||
Waardenburg syndrome type 1 | ||||||||
Waardenburg syndrome type 3 |
Mouse Phenotypes | nervous system phenotype |
increased embryonic neuroepithelium apoptosis |
abnormal neural tube morphology |
delayed neural tube closure |
incomplete rostral neuropore closure |
open neural tube |
spina bifida |
spina bifida cystica |
caudal rachischisis |
small embryonic telencephalon |
abnormal midbrain development |
abnormal brain ventricle morphology |
abnormal lateral ventricle morphology |
abnormal hindbrain morphology |
exencephaly |
abnormal dorsal root ganglion morphology |
absent dorsal root ganglion |
disorganized dorsal root ganglion |
abnormal spinal cord morphology |
|
Availability | Mouse Genotype | |||||||||||||||||||
Pax3Rwa/Pax3Rwa | ||||||||||||||||||||
Pax3Sp-1H/Pax3Sp-1H | ||||||||||||||||||||
Pax3Sp-1Wli/Pax3Sp-1Wli | ||||||||||||||||||||
Pax3Sp-1Xzg/Pax3Sp-1Xzg | ||||||||||||||||||||
Pax3Sp-2H/Pax3Sp-2H | ! | |||||||||||||||||||
Pax3Sp-5H/Pax3Sp-5H | * | |||||||||||||||||||
Pax3Sp-7H/Pax3Sp-7H | ||||||||||||||||||||
Pax3Sp-d/Pax3Sp-d | ||||||||||||||||||||
Pax3Sp/Pax3Sp | ||||||||||||||||||||
Pax3tm1(cre)Joe/Pax3tm1(cre)Joe | ||||||||||||||||||||
Pax3tm1Buck/Pax3tm1Buck | ||||||||||||||||||||
Pax3tm2Joe/Pax3tm2Joe | ||||||||||||||||||||
Pax3tm3(Pax7)Buck/Pax3tm3(Pax7)Buck | ||||||||||||||||||||
Pax3tm6.2Buck/Pax3tm6.2Buck | ||||||||||||||||||||
Pax3Rwa/Pax3+ | ||||||||||||||||||||
Pax3Sp/Pax3+ | ||||||||||||||||||||
Pax3tm1Buck/Pax3Sp | ||||||||||||||||||||
Gt(ROSA)26Sortm2(Pax3)Joe/Gt(ROSA)26Sortm2(Pax3)Joe Pax3tm1(cre)Joe/Pax3+ (conditional) |
* | |||||||||||||||||||
Pax3tm2Joe/Pax3tm2Joe H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
||||||||||||||||||||
Pax3tm5.1Buck/Pax3+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 06/12/2024 MGI 6.13 |
|
|