Symbol Name ID |
Pdgfrb
platelet derived growth factor receptor, beta polypeptide MGI:97531 |
Darker colors indicate more annotations |
Human Phenotypes | Calcification of the small brain vessels |
Cerebellar calcifications |
Cerebellar dentate nucleus calcification |
Cerebral calcification |
Basal ganglia calcification |
Thalamic calcification |
Benign neoplasm of the central nervous system |
Dysdiadochokinesis |
Limb dysmetria |
Bradykinesia |
Parkinsonism |
Athetosis |
Chorea |
Tremor |
Postural tremor |
Hand tremor |
Abnormal pyramidal sign |
Hemiplegia/hemiparesis |
Dysarthria |
Depression |
Anxiety |
Psychosis |
Bipolar affective disorder |
Apathy |
Impaired executive functioning |
Motor tics |
Attention deficit hyperactivity disorder |
Cognitive impairment |
Memory impairment |
Mental deterioration |
Dementia |
Micrographia |
Hyperreflexia |
Dyskinesia |
Dystonia |
Gait disturbance |
Postural instability |
Migraine |
Global developmental delay |
Seizure |
Disease(s) Associated with PDGFRB | ||||||||||||||||||||||||||||||||||||||||
basal ganglia calcification | ||||||||||||||||||||||||||||||||||||||||
infantile myofibromatosis |
Mouse Phenotypes | intracranial hemorrhage |
increased susceptibility to neuronal excitotoxicity |
decreased neuron number |
decreased retina ganglion cell number |
retina ganglion cell degeneration |
abnormal blood-retina barrier function |
abnormal nervous system electrophysiology |
reduced sensorimotor gating |
decreased prepulse inhibition |
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Availability | Mouse Genotype | |||||||||
Pdgfrbredeye/Pdgfrbredeye | ||||||||||
Pdgfrbtm10Sor/Pdgfrbtm10Sor | ||||||||||
Pdgfrbtm1Msas/Pdgfrbtm1Msas Tg(Nes-cre)1Nogu/? (conditional) |
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Pdgfrbtm1Msas/Pdgfrbtm1Msas Tg(Nes-cre)1Nogu/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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