Symbol Name ID |
Sox4
SRY (sex determining region Y)-box 4 MGI:98366 |
Darker colors indicate more annotations |
Human Phenotypes | Microcephaly |
Spastic tetraparesis |
Cerebellar atrophy |
Delayed speech and language development |
Intellectual disability |
Global developmental delay |
Delayed ability to walk |
Disease(s) Associated with SOX4 | |||||||
Coffin-Siris syndrome 10 |
Mouse Phenotypes | abnormal axon fasciculation |
abnormal neural tube morphology |
abnormal neural tube closure |
abnormal sympathetic ganglion morphology |
abnormal brain morphology |
abnormal hindbrain development |
decreased brain size |
abnormal nervous system development |
decreased amacrine cell number |
decreased retina ganglion cell number |
abnormal retina bipolar cell morphology |
optic nerve hypoplasia |
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Availability | Mouse Genotype | ||||||||||||
Sox4em1(IMPC)Mbp/Sox4em1(IMPC)Mbp | |||||||||||||
Sox4em1(IMPC)Mbp/Sox4+ | |||||||||||||
Sox4tm1Vlf/Sox4tm1Vlf Tg(Dbh-icre)1Gsc/0 (conditional) |
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Sox4tm1Vlf/Sox4tm1Vlf Tg(Six3-cre)69Frty/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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