Symbol Name ID |
Thrb
thyroid hormone receptor beta MGI:98743 |
Darker colors indicate more annotations |
Human Phenotypes | Delayed speech and language development |
Attention deficit hyperactivity disorder |
Disease(s) Associated with THRB | ||
thyroid hormone resistance syndrome |
Mouse Phenotypes | audiogenic seizures |
increased thyrotroph cell number |
enlarged pituitary gland |
increased pituitary adenoma incidence |
abnormal pituitary gland physiology |
decreased cochlear outer hair cell number |
cochlear outer hair cell degeneration |
short cochlear outer hair cells |
cochlear hair cell degeneration |
abnormal cochlear inner hair cell physiology |
abnormal cochlear outer hair cell physiology |
decreased cochlear microphonics |
decreased cochlear outer hair cell electromotility |
abnormal cochlear nerve compound action potential |
abnormal cerebellar Purkinje cell layer |
abnormal Purkinje cell morphology |
decreased Purkinje cell number |
thin cerebellar molecular layer |
small cerebellum |
abnormal retina cone cell morphology |
impaired synaptic plasticity |
decreased excitatory postsynaptic current amplitude |
reduced long-term potentiation |
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Availability | Mouse Genotype | |||||||||||||||||||||||
Thrbtm1.1Syc/Thrbtm1.1Syc | ||||||||||||||||||||||||
Thrbtm1Df/Thrbtm1Df | ||||||||||||||||||||||||
Thrbtm1Ehs/Thrbtm1Ehs | ||||||||||||||||||||||||
Thrbtm2Df/Thrbtm2Df | ||||||||||||||||||||||||
Thrbtm2Few/Thrbtm2Few | ||||||||||||||||||||||||
Thrbtm3Few/Thrbtm3Few | ||||||||||||||||||||||||
Thrbtm4Few/Thrbtm4Few | ||||||||||||||||||||||||
Thrbtm1.1Syc/Thrb+ | ||||||||||||||||||||||||
Thrbtm2Few/Thrb+ | ||||||||||||||||||||||||
Thrbtm1Df/Thrbtm1Mkni Tg(Pres-cre)1Jnz/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 06/12/2024 MGI 6.13 |
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