Symbol Name ID |
Umod
uromodulin MGI:102674 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Hematuria |
Decreased urinary urate |
Proteinuria |
Hyposthenuria |
Vesicoureteral reflux |
Thickened glomerular basement membrane |
IgA deposition in the glomerulus |
Glomerular sclerosis |
Focal segmental glomerulosclerosis |
Renal tubular atrophy |
Tubulointerstitial fibrosis |
Tubulointerstitial nephritis |
Reduced renal corticomedullary differentiation |
Renal corticomedullary cysts |
Hyperechogenic kidneys |
Abnormal renal insterstitial morphology |
Renal interstitial fibrosis |
Renal cyst |
Renal hypoplasia |
Decreased glomerular filtration rate |
Polyuria |
Nephritis |
Renal insufficiency |
Chronic kidney disease |
Stage 1 chronic kidney disease |
Stage 2 chronic kidney disease |
Stage 3 chronic kidney disease |
Stage 4 chronic kidney disease |
Stage 5 chronic kidney disease |
Impaired renal concentrating ability |
Disease(s) Associated with UMOD | ||||||||||||||||||||||||||||||
familial juvenile hyperuricemic nephropathy |
Mouse Phenotypes | renal/urinary system phenotype |
increased kidney apoptosis |
increased kidney cell proliferation |
kidney corticomedullary cyst |
renal glomerulus cyst |
decreased urine creatinine level |
increased urine creatinine level |
increased urine ammonia level |
increased urine calcium level |
increased urine chloride ion level |
increased urine potassium level |
decreased urine sodium level |
increased urine sodium level |
abnormal urine organic anion level |
decreased urine citrate level |
abnormal urine homeostasis |
increased urine magnesium level |
abnormal urine osmolality |
decreased urine osmolality |
decreased urine pH |
increased urine phosphate level |
decreased urine protein level |
abnormal urine urea nitrogen level |
decreased urine uric acid level |
increased urine uric acid level |
crystalluria |
kidney inflammation |
abnormal kidney morphology |
abnormal papillary duct morphology |
dilated kidney collecting duct |
abnormal juxtaglomerular apparatus morphology |
dilated renal glomerular capsule |
glomerulosclerosis |
renal interstitial fibrosis |
abnormal kidney papilla morphology |
hydronephrosis |
decreased kidney weight |
renal tubule atrophy |
abnormal renal tubule morphology |
abnormal loop of Henle ascending limb thick segment morphology |
abnormal proximal convoluted tubule morphology |
dilated renal tubule |
renal tubular necrosis |
renal cast |
nephrocalcinosis |
renal fibrosis |
urolithiasis |
abnormal renal/urinary system physiology |
decreased creatinine clearance |
increased creatinine clearance |
decreased renal glomerular filtration rate |
increased renal glomerular filtration rate |
isosthenuria |
kidney failure |
decreased urine flow rate |
increased urine flow rate |
polyuria |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Umodtm1.1Rvt/Umodtm1.1Rvt | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Umodtm1Kuma/Umodtm1Kuma | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Umodtm1Xrw/Umodtm1Xrw | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
UmodUrehd1/UmodUrehd1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Umodurehr4/Umodurehr4 | * | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Umodem1Duf/Umod+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Umodtm1.1Rvt/Umod+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Umodtm1Xrw/Umod+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
UmodUrehd1/Umod+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Umodurehr4/Umod+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Tg(Umod*C147W)958Lura/0 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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