Symbol Name ID |
Myo1e
myosin IE MGI:106621 |
Darker colors indicate more annotations |
Human Phenotypes | Hematuria |
Proteinuria |
Focal segmental glomerulosclerosis |
Renal tubular atrophy |
Nephrotic syndrome |
Stage 5 chronic kidney disease |
Disease(s) Associated with MYO1E | ||||||
focal segmental glomerulosclerosis 6 |
Mouse Phenotypes | abnormal glomerular capillary morphology |
enlarged kidney |
increased kidney weight |
abnormal urine homeostasis |
increased urine protein level |
albuminuria |
hemoglobinuria |
hematuria |
leukocyturia |
abnormal podocyte foot process morphology |
podocyte foot process effacement |
podocyte microvillus transformation |
abnormal renal glomerulus basement membrane morphology |
increased renal glomerulus basement membrane thickness |
abnormal renal glomerulus morphology |
expanded mesangial matrix |
glomerulosclerosis |
renal interstitial fibrosis |
abnormal proximal convoluted tubule morphology |
proximal convoluted tubule brush border loss |
renal cast |
pale kidney |
abnormal renal glomerular filtration rate |
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Availability | Mouse Genotype | |||||||||||||||||||||||
Myo1etm1.1Flv/Myo1etm1.1Flv | ||||||||||||||||||||||||
Myo1etm1Flv/Myo1etm1Flv Tg(NPHS2-cre)295Lbh/0 (conditional) |
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Myo1etm1Flv/Myo1etm1.1Flv Tg(NPHS2-cre)295Lbh/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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