Symbol Name ID |
Atp6ap2
ATPase, H+ transporting, lysosomal accessory protein 2 MGI:1917745 |
Darker colors indicate more annotations |
Mouse Phenotypes | increased podocyte apoptosis |
kidney cyst |
kidney cortex cyst |
kidney medulla cyst |
decreased urine osmolality |
increased urine pH |
increased urine protein level |
albuminuria |
abnormal kidney collecting duct morphology |
dilated kidney collecting duct |
abnormal kidney cortex morphology |
abnormal podocyte morphology |
podocyte foot process effacement |
abnormal renal glomerulus morphology |
glomerulosclerosis |
abnormal kidney development |
abnormal metanephric mesenchyme morphology |
abnormal metanephric ureteric bud development |
abnormal nephrogenic zone morphology |
abnormal renal tubule epithelium morphology |
decreased kidney weight |
small kidney |
renal hypoplasia |
abnormal nephron morphology |
abnormal nephron morphogenesis |
abnormal S-shaped body morphology |
abnormal comma shaped body morphology |
decreased nephron number |
absent proximal convoluted tubule brush border |
dilated renal tubule |
renal cast |
abnormal ureteric bud morphology |
impaired branching involved in ureteric bud morphogenesis |
decreased urine output |
polyuria |
|
Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||
Atp6ap2em1Nira/Y | ||||||||||||||||||||||||||||||||||||
Atp6ap2tm1.1Aich/Atp6ap2tm1.1Aich Tg(Hoxb7-cre)5526Cmb/0 (conditional) |
||||||||||||||||||||||||||||||||||||
Atp6ap2tm1.1Aich/Atp6ap2tm1.1Aich Tg(Six2-EGFP/cre)1Amc/0 (conditional) |
||||||||||||||||||||||||||||||||||||
Atp6ap2tm1.1Aich/Atp6ap2+ Tg(Six2-EGFP/cre)1Amc/0 (conditional) |
||||||||||||||||||||||||||||||||||||
Atp6ap2tm1.1Ics/Y Tg(NPHS2-cre)295Lbh/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 07/05/2024 MGI 6.24 |
|
|