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Symbol Name ID |
Pbx1
pre B cell leukemia homeobox 1 MGI:97495 |
| Darker colors indicate more annotations |
| Human Phenotypes | Vesicoureteral reflux |
Ectopic kidney |
Horseshoe kidney |
Decreased numbers of nephrons |
Absence of renal corticomedullary differentiation |
Hyperechogenic kidneys |
Renal dysplasia |
Renal agenesis |
Unilateral renal agenesis |
Renal hypoplasia |
Renal insufficiency |
Bifid ureter |
| Disease(s) Associated with PBX1 | ||||||||||||
| congenital anomalies of kidney and urinary tract syndrome with or without hearing loss, abnormal ears, or developmental delay |
| Mouse Phenotypes | abnormal kidney cortex morphology |
decreased renal glomerulus number |
abnormal metanephric mesenchyme morphology |
abnormal nephrogenic mesenchyme morphogenesis |
abnormal metanephros morphology |
abnormal nephrogenic zone morphology |
delayed kidney development |
abnormal kidney medulla morphology |
small kidney |
renal hypoplasia |
decreased nephron number |
ectopic kidney |
pelvic kidney |
single kidney |
impaired branching involved in ureteric bud morphogenesis |
abnormal ureteric bud elongation |
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| Availability | Mouse Genotype | ||||||||||||||||
| Pbx1em1Dunw/Pbx1em1Dunw | |||||||||||||||||
| Pbx1tm1Mlc/Pbx1tm1Mlc | |||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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