Symbol
Name
ID

Lamb2
laminin, beta 2
MGI:99916

Phenotype annotations related to renal/urinary system

Darker colors indicate more annotations

Human Phenotypes

Hematuria

Proteinuria

Renal interstitial foam cells

Podocyte foot process effacement

Mesangial hypercellularity

Diffuse mesangial sclerosis

Focal segmental glomerulosclerosis

Glomerulonephritis

Hyperechogenic kidneys

Nephrotic syndrome

Renal insufficiency

Stage 5 chronic kidney disease

Disease(s) Associated with LAMB2

nephrotic syndrome type 5

Pierson syndrome

Mouse Phenotypes		increased urine protein level	albuminuria	glomerulonephritis	abnormal kidney morphology	fused podocyte foot processes	abnormal renal glomerulus basement membrane morphology	increased renal glomerulus basement membrane thickness	abnormal renal tubule epithelium morphology	abnormal kidney physiology	abnormal glomerular filtration barrier function
Availability	Mouse Genotype	increased urine protein level	albuminuria	glomerulonephritis	abnormal kidney morphology	fused podocyte foot processes	abnormal renal glomerulus basement membrane morphology	increased renal glomerulus basement membrane thickness	abnormal renal tubule epithelium morphology	abnormal kidney physiology	abnormal glomerular filtration barrier function
	Lamb2^npht/Lamb2^npht
	Lamb2^tm1Jrs/Lamb2^tm1Jrs

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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