Symbol Name ID |
Ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit MGI:107940 |
Darker colors indicate more annotations |
Human Phenotypes | Cryptorchidism |
Hydrocele testis |
Uterine leiomyosarcoma |
Disease(s) Associated with EZH2 | |||
colorectal cancer | |||
Weaver syndrome |
Mouse Phenotypes | decreased uterine NK cell number |
impaired mammary gland growth during pregnancy |
abnormal endometrial gland morphology |
increased endometrial gland number |
abnormal endometrium morphology |
endometrium hyperplasia |
enlarged uterine horn |
abnormal uterine epithelium development |
abnormal parturition |
dystocia |
reduced female fertility |
decreased litter size |
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Availability | Mouse Genotype | ||||||||||||
Gt(ROSA)26Sortm4(H1/tetO-RNAi:Ezh2)Arte/Gt(ROSA)26Sor+ | |||||||||||||
Gt(ROSA)26Sortm5(H1/tetO-RNAi:Ezh2)Arte/Gt(ROSA)26Sor+ | |||||||||||||
Ezh2tm2Sho/Ezh2tm2Sho Pgrtm2(cre)Lyd/Pgr+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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