Symbol Name ID |
Npc1
NPC intracellular cholesterol transporter 1 MGI:1097712 |
Darker colors indicate more annotations |
Mouse Phenotypes | absent sperm flagellum |
oligozoospermia |
teratozoospermia |
abnormal sperm head morphology |
absent sperm head |
decreased endometrial gland number |
abnormal ovary morphology |
absent corpus luteum |
abnormal ovarian follicle morphology |
abnormal granulosa cell morphology |
absent mature ovarian follicles |
decreased secondary ovarian follicle number |
decreased tertiary ovarian follicle number |
abnormal tertiary ovarian follicle morphology |
decreased ovary weight |
small ovary |
seminiferous tubule degeneration |
decreased ovary secretion |
abnormal female reproductive system morphology |
endometrium atrophy |
thin endometrium |
thin myometrium |
thin uterus |
uterus atrophy |
arrest of spermatogenesis |
decreased superovulation rate |
anovulation |
absent estrous cycle |
female infertility |
infertility |
male infertility |
reduced fertility |
impaired fertilization |
impaired binding of sperm to zona pellucida |
abnormal sperm physiology |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||
Npc1m1N/Npc1m1N | ||||||||||||||||||||||||||||||||||||
Npc1nmf164/Npc1nmf164 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/02/2024 MGI 6.13 |
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