Symbol Name ID |
Fbxw7
F-box and WD-40 domain protein 7 MGI:1354695 |
Darker colors indicate more annotations |
Human Phenotypes | Cryptorchidism |
Disease(s) Associated with FBXW7 | |
developmental delay, hypotonia, and impaired language |
Mouse Phenotypes | oligozoospermia |
decreased male germ cell number |
increased male germ cell apoptosis |
abnormal male germ cell physiology |
abnormal seminiferous tubule epithelium morphology |
abnormal Sertoli cell barrier morphology |
abnormal Sertoli cell morphology |
decreased Sertoli cell number |
ectopic Sertoli cells |
seminiferous tubule degeneration |
abnormal testis development |
decreased testis weight |
small testis |
testicular atrophy |
testis degeneration |
arrest of spermatogenesis |
abnormal epididymis morphology |
decreased epididymis weight |
small epididymis |
decreased litter size |
male infertility |
reduced male fertility |
|
Availability | Mouse Genotype | ||||||||||||||||||||||
Fbxw7tm1Iaai/Fbxw7tm1Iaai Tg(Amh-cre)8815Reb/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 08/02/2024 MGI 6.24 |
![]() |
|