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Symbol
Name
ID
Otx2
orthodenticle homeobox 2
MGI:97451
Phenotype annotations related to reproductive system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Hypogonadotropic hypogonadism
Micropenis
Decreased testicular size
Cryptorchidism
Amenorrhea
Infertility
Disease(s) Associated with OTX2
panhypopituitarism
syndromic microphthalmia 5

Mouse Phenotypes
reproductive system phenotype
decreased testis weight
decreased litter size
reduced fertility
reduced male fertility
Availability Mouse Genotype
Otx2tm2Asim/Otx2tm2Asim
Otx2tm8Asim/Otx2tm8Asim *
Otx2tm1Pas/Otx2+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory