Symbol Name ID |
Sry
sex determining region of Chr Y MGI:98660 |
* | Aspects of the system are reported to show a normal phenotype. |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Hypergonadotropic hypogonadism |
Abnormal female external genitalia morphology |
Clitoral hypertrophy |
Abnormal male external genitalia morphology |
Hypospadias |
Male pseudohermaphroditism |
Ambiguous genitalia |
Ovotestis |
True hermaphroditism |
Bicornuate uterus |
Gonadal dysgenesis |
Gonadal dysgenesis with female appearance, male |
Gonadoblastoma |
Sex reversal |
Abnormality of the menstrual cycle |
Primary amenorrhea |
Azoospermia |
Disease(s) Associated with SRY | |||||||||||||||||
46,XX sex reversal 1 | |||||||||||||||||
46,XY sex reversal | |||||||||||||||||
46,XY sex reversal 1 |
Mouse Phenotypes | reproductive system phenotype |
abnormal ovarian follicle morphology |
decreased tertiary ovarian follicle number |
abnormal spermatogenesis |
ovotestis |
abnormal primary sex determination |
primary sex reversal |
true hermaphroditism |
abnormal secondary sex determination |
secondary sex reversal |
sex reversal |
prolonged estrus |
female infertility |
infertility |
|
Availability | Mouse Genotype | ||||||||||||||
X/SryAKR/J | * | ||||||||||||||
X/SryAKR/JSryRIII | *! | ||||||||||||||
X/SryCB | |||||||||||||||
X/Srydl1Rlb | |||||||||||||||
X/Srydl1Rlb Tg(Sry)2Ei/0 |
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X/Sryem1Takas | |||||||||||||||
X/SryPOS | |||||||||||||||
Tg(Sry)1Ei/0 | |||||||||||||||
Tg(Sry)1Rlb/0 | |||||||||||||||
Tg(Sry)2Ei/0 | |||||||||||||||
Tg(Sry)3Ei/0 | |||||||||||||||
Tg(Sry)4Ei/0 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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