Symbol
Name
ID

Abca3
ATP-binding cassette, sub-family A member 3
MGI:1351617

Phenotype annotations related to respiratory system

Darker colors indicate more annotations

Human Phenotypes	Acute infectious pneumonia	Hypoxemia	Crackles	Respiratory distress	Tachypnea	Crazy paving pattern	Restrictive ventilatory defect	Cough	Respiratory failure requiring assisted ventilation
Disease(s) Associated with ABCA3
pulmonary alveolar proteinosis

Mouse Phenotypes

pulmonary vascular congestion

pulmonary alveolar hemorrhage

abnormal lung development

abnormal lung saccule morphology

thick lung-associated mesenchyme

abnormal bronchiole epithelium morphology

absent type I pneumocytes

abnormal type II pneumocyte morphology

abnormal alveolar lamellar body morphology

absent alveolar lamellar bodies

decreased alveolar lamellar body number

increased wet-to-dry lung weight ratio

abnormal pulmonary alveolus morphology

atelectasis

primary atelectasis

thick pulmonary interalveolar septum

respiratory distress

respiratory failure

abnormal surfactant physiology

abnormal surfactant composition

abnormal surfactant secretion

Availability

Mouse Genotype

Abca3^tm1Dgen/Abca3^tm1Dgen

Abca3^tm1Frm/Abca3^tm1Frm

Abca3^tm1Holz/Abca3^tm1Holz

Abca3^tm1Nina/Abca3^tm1Nina

Abca3^tm1Dgen/Abca3⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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