Symbol Name ID |
Shh
sonic hedgehog MGI:98297 |
Darker colors indicate more annotations |
Human Phenotypes | Abnormal nasopharynx morphology |
Aplasia/Hypoplasia of the lungs |
Respiratory insufficiency |
Disease(s) Associated with SHH | |||
holoprosencephaly | |||
solitary median maxillary central incisor |
Mouse Phenotypes | abnormal lung vasculature morphology |
abnormal nasal bone morphology |
abnormal nasal pit morphology |
tracheoesophageal fistula |
lung cyst |
abnormal tracheal smooth muscle morphology |
abnormal respiratory system morphology |
abnormal lung morphology |
abnormal lung development |
abnormal branching involved in lung morphogenesis |
impaired branching involved in bronchus morphogenesis |
abnormal lung saccule morphology |
impaired lung lobe morphogenesis |
pulmonary hypoplasia |
abnormal respiratory conducting tube morphology |
abnormal bronchus morphology |
abnormal pharynx morphology |
abnormal trachea morphology |
abnormal tracheal cartilage morphology |
decreased tracheal cartilage ring number |
absent tracheal cartilage rings |
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Availability | Mouse Genotype | |||||||||||||||||||||
Shhtm1(EGFP/cre)Cjt/Shhtm1(EGFP/cre)Cjt | ||||||||||||||||||||||
Shhtm1Amc/Shhtm1Amc | ||||||||||||||||||||||
Shhtm1Chg/Shhtm1Chg | ||||||||||||||||||||||
Shhtm3(cre)Chg/Shhtm3(cre)Chg | ||||||||||||||||||||||
Shhtm2Amc/Shhtm2Amc Tg(SFTPC-rtTA)5Jaw/0 Tg(tetO-cre)1Jaw/0 (conditional) |
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Shhtm1Amc/Shhtm2Amc Tg(SFTPC-rtTA)5Jaw/0 Tg(tetO-cre)1Jaw/0 (conditional) |
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Shhtm1Amc/Shhtm2Amc Tg(KRT14-cre)1Amc/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 06/12/2024 MGI 6.13 |
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