Symbol Name ID |
Tgfb1
transforming growth factor, beta 1 MGI:98725 |
Darker colors indicate more annotations |
Human Phenotypes | Sinusitis |
Chronic sinusitis |
Pleural effusion |
Recurrent pneumonia |
Asthma |
Recurrent respiratory infections |
Recurrent bronchopulmonary infections |
Recurrent lower respiratory tract infections |
Bronchoconstriction |
Pneumothorax |
Emphysema |
Chronic bronchitis |
Hemoptysis |
Bronchiectasis |
Decreased forced expiratory flow 25-75% |
Reduced forced expiratory volume in one second |
Reduced forced vital capacity |
Airway hyperresponsiveness |
Airway obstruction |
Chronic pulmonary obstruction |
Chronic lung disease |
Hyperpolarized transepithelial nasal potential difference |
Disease(s) Associated with TGFB1 | ||||||||||||||||||||||
asthma | ||||||||||||||||||||||
atopic dermatitis | ||||||||||||||||||||||
chronic obstructive pulmonary disease | ||||||||||||||||||||||
cystic fibrosis | ||||||||||||||||||||||
multiple myeloma | ||||||||||||||||||||||
pulmonary emphysema |
Mouse Phenotypes | lung inflammation |
interstitial pneumonia |
abnormal lung morphology |
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Availability | Mouse Genotype | |||
Tgfb1tm1Doe/Tgfb1tm1Doe | ||||
Tgfb1tm1N/Tgfb1tm1N | ||||
Tgfb1tm1Rif/Tgfb1tm1Rif | ||||
Tg(Lck-cre)548Jxm/? Tgfb1tm2.1Doe/Tgfb1tm2.1Doe (conditional) |
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B9d2/Tgfb1tm1Flv/Tgfb1tm2Flv Tg(Cd4-cre)1Cwi/0 (conditional) |
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B9d2/Tgfb1tm1Flv/Tgfb1tm2Flv Tnfrsf4tm2(cre)Nik/Tnfrsf4+ (conditional) |
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Tgfb1tm1Doe/Tgfb1tm2.1Doe Tg(Lck-cre)548Jxm/? (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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