Symbol Name ID |
Lmx1b
LIM homeobox transcription factor 1 beta MGI:1100513 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Enamel hypoplasia |
Abnormal digit morphology |
Clinodactyly of the 5th finger |
Absent distal interphalangeal creases |
Contracture of the distal interphalangeal joint of the fingers |
Proximal finger joint hyperextensibility |
Abnormal femur morphology |
Disproportionate prominence of the femoral medial condyle |
Abnormal tibia morphology |
Patellar aplasia |
Patellar hypoplasia |
Dislocated radial head |
Hypoplastic radial head |
Elongated radius |
Achilles tendon contracture |
Abnormality of the knee |
Abnormal patella morphology |
Patellar dislocation |
Knee flexion contracture |
Knee joint hypermobility |
Abnormality of the elbow |
Cubitus valgus |
Elbow flexion contracture |
Limited elbow extension |
Limited pronation/supination of forearm |
Antecubital pterygium |
Flexion contracture |
Osteochondritis dissecans |
Knee pain |
Iliac horns |
Glenoid fossa hypoplasia |
Hypoplasia of first ribs |
Thickening of the lateral border of the scapula |
Pectus excavatum |
Lumbar hyperlordosis |
Scoliosis |
Back pain |
Spondylolisthesis |
Spondylolysis |
Reduced bone mineral density |
Osteoporosis |
Arthritis |
Disease(s) Associated with LMX1B | ||||||||||||||||||||||||||||||||||||||||||
nail-patella syndrome |
Mouse Phenotypes | skeleton phenotype |
abnormal cranial suture morphology |
abnormal fontanelle morphology |
abnormal interparietal bone morphology |
absent supraoccipital bone |
absent ulna |
abnormal ankle joint morphology |
absent patella |
abnormal metacarpal bone morphology |
abnormal tendon morphology |
abnormal skeleton morphology |
abnormal clavicle morphology |
abnormal pectoral girdle bone morphology |
small scapula |
absent ilium |
abnormal cartilage development |
abnormal joint morphology |
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Availability | Mouse Genotype | |||||||||||||||||
Lmx1btm1Rjo/Lmx1btm1Rjo | ||||||||||||||||||
Gt(ROSA)26Sortm1(CAG-Lmx1b,ALPP)Rjo/Gt(ROSA)26Sor+ Sox9tm3(cre)Crm/Sox9+ (conditional) |
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Gt(ROSA)26Sortm1(CAG-Lmx1b,ALPP)Rjo/Gt(ROSA)26Sor+ Tg(Prrx1-cre)1Cjt/0 (conditional) |
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Lmx1btm1Rjo/Lmx1btm1Zfc Sox9tm3(cre)Crm/Sox9+ (conditional) |
* | |||||||||||||||||
Lmx1btm1Rjo/Lmx1btm1Zfc Tg(Prrx1-cre)1Cjt/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/27/2024 MGI 6.24 |
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