Symbol Name ID |
Kl
klotho MGI:1101771 |
Darker colors indicate more annotations |
Human Phenotypes | Cervical spondylosis |
Spondylolisthesis |
Spondylolysis |
Osteoporosis |
Gout |
Osteoarthritis |
Disease(s) Associated with KL | ||||||
coronary artery disease | ||||||
spondylosis |
Mouse Phenotypes | abnormal osteoblast physiology |
thick zygomatic arch |
abnormal middle ear ossicle morphology |
abnormal incus morphology |
abnormal malleus morphology |
abnormal malleus manubrium morphology |
short malleus manubrium |
short malleus |
small stapes obturator foramen |
decreased osteoclast cell number |
abnormal osteoclast morphology |
abnormal femur morphology |
decreased femur compact bone thickness |
short femur |
short tibia |
abnormal tracheal cartilage morphology |
abnormal long bone epiphyseal plate proliferative zone |
decreased width of hypertrophic chondrocyte zone |
decreased long bone epiphyseal plate size |
abnormal long bone epiphysis morphology |
small pubis |
abnormal rib morphology |
wide ribs |
kyphosis |
kyphoscoliosis |
abnormal vertebrae morphology |
abnormal bone structure |
decreased bone mineral content |
abnormal bone mineral density |
decreased bone mineral density of femur |
decreased bone mineral density |
decreased compact bone thickness |
abnormal osteoblast morphology |
decreased osteoblast cell number |
abnormal trabecular bone morphology |
absent bone trabeculae |
osteoporosis |
osteopetrosis |
abnormal bone ossification |
decreased bone ossification |
decreased bone resorption |
|
Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||
Klecalc1/Klecalc1 | ||||||||||||||||||||||||||||||||||||||||||
Klecalc2/Klecalc2 | ||||||||||||||||||||||||||||||||||||||||||
Klem1Btlr/Klem1Btlr | ||||||||||||||||||||||||||||||||||||||||||
Klkl/Klkl | ||||||||||||||||||||||||||||||||||||||||||
Klm1Anu/Klm1Anu | ||||||||||||||||||||||||||||||||||||||||||
Kltm1.2Tel/Kltm1.2Tel | ||||||||||||||||||||||||||||||||||||||||||
Kltm1Lex/Kltm1Lex | ||||||||||||||||||||||||||||||||||||||||||
Kltm1Yin/Kltm1Yin | ||||||||||||||||||||||||||||||||||||||||||
Klkl/Kl+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 08/02/2024 MGI 6.24 |
|
|