Symbol Name ID |
Casr
calcium-sensing receptor MGI:1351351 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Chondrocalcinosis |
Reduced bone mineral density |
Osteopenia |
Generalized osteoporosis |
Basal ganglia calcification |
Disease(s) Associated with CASR | |||||
autosomal dominant hypocalcemia | |||||
autosomal dominant hypocalcemia 1 | |||||
hyperparathyroidism |
Mouse Phenotypes | skeleton phenotype |
abnormal skeleton morphology |
increased width of hypertrophic chondrocyte zone |
kyphoscoliosis |
decreased bone mineral content |
decreased bone mineral density |
decreased compact bone volume |
decreased trabecular bone volume |
decreased compact bone thickness |
abnormal trabecular bone morphology |
decreased bone trabecula number |
decreased trabecular bone connectivity density |
decreased trabecular bone thickness |
abnormal skeleton development |
abnormal bone mineralization |
decreased bone mineralization |
rickets |
delayed bone ossification |
fragile skeleton |
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Availability | Mouse Genotype | |||||||||||||||||||
Casrtm1Ces/Casrtm1Ces | ||||||||||||||||||||
Casrtm1Ces/Casr+ | * | |||||||||||||||||||
Casrtm1Wch/Casrtm1Wch Tg(PTH-cre)4167Slib/0 (conditional) |
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Casrtm1Wch/Casrtm1Wch Tg(Col1a1-cre)2Bek/0 (conditional) |
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Casrtm1Wch/Casrtm1Wch Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 (conditional) |
* | |||||||||||||||||||
Casrtm1Wch/Casrtm1Wch Tg(Col2a1-cre)1Bhr/0 (conditional) |
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Casrtm1Wch/Casrtm1Wch Tg(Col2a1-cre/ERT)KA3Smac/0 (conditional) |
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Casrtm1Wch/Casr+ Tg(PTH-cre)4167Slib/0 (conditional) |
* |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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