Symbol Name ID |
Gli2
GLI-Kruppel family member GLI2 MGI:95728 |
Darker colors indicate more annotations |
Human Phenotypes | Hypoplasia of the premaxilla |
Hypoplasia of the maxilla |
Malar flattening |
Microcephaly |
Wide anterior fontanel |
Short neck |
Postaxial hand polydactyly |
Postaxial polydactyly |
Disease(s) Associated with GLI2 | ||||||||
Culler-Jones syndrome | ||||||||
holoprosencephaly 9 |
Mouse Phenotypes | abnormal basioccipital bone morphology |
abnormal basisphenoid bone morphology |
abnormal frontal bone morphology |
abnormal parietal bone morphology |
absent presphenoid bone |
absent lower incisors |
absent upper incisors |
small mandibular condyloid process |
absent temporomandibular joint disk |
small mandible |
absent maxillary shelf |
short maxilla |
absent palatine bone horizontal plate |
short humerus |
bowed radius |
short radius |
short ulna |
short femur |
short fibula |
short tibia |
abnormal tracheal cartilage morphology |
abnormal long bone morphology |
abnormal long bone epiphyseal plate proliferative zone |
decreased width of hypertrophic chondrocyte zone |
increased width of hypertrophic chondrocyte zone |
decreased length of long bones |
short sternum |
increased rib number |
absent intervertebral disk |
abnormal spine curvature |
abnormal vertebral body morphology |
abnormal cartilage development |
decreased chondrocyte number |
abnormal epiphyseal plate morphology |
delayed bone ossification |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||
Gli2tm1Alj/Gli2tm1Alj | ||||||||||||||||||||||||||||||||||||
Gt(ROSA)26Sortm2(Gli2*)Flng/Gt(ROSA)26Sor+ Tg(Col2a1-cre)3Amc/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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