Symbol Name ID |
Ptpn2
protein tyrosine phosphatase, non-receptor type 2 MGI:97806 |
* | Aspects of the system are reported to show a normal phenotype. |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Mouse Phenotypes | skeleton phenotype |
abnormal osteoclast differentiation |
abnormal osteoclast physiology |
decreased diameter of femur |
short femur |
abnormal skeleton morphology |
abnormal long bone morphology |
abnormal long bone epiphyseal ossification zone morphology |
decreased long bone epiphyseal plate size |
abnormal bone structure |
decreased bone mineral content |
decreased bone mineral density |
increased bone mineral density |
decreased trabecular bone volume |
increased trabecular bone volume |
abnormal bone trabecula morphology |
decreased bone trabecula number |
increased bone trabecula number |
abnormal ossification involved in bone maturation |
increased bone resorption |
|
Availability | Mouse Genotype | ||||||||||||||||||||
Ptpn2tm1Mtr/Ptpn2tm1Mtr | *! | ! | |||||||||||||||||||
Ptpn2tm2.1Ttig/Ptpn2tm2.1Ttig | * | ||||||||||||||||||||
Ptpn2tm1.1Kry/Ptpn2tm1.1Kry Tg(Col1a1-cre)1Kry/0 (conditional) |
* | ||||||||||||||||||||
Ptpn2tm1.1Ttig/Ptpn2tm1.1Ttig Tg(Nes-cre)1Kln/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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