Symbol Name ID |
Fscn2
fascin actin-bundling protein 2 MGI:2443337 |
Darker colors indicate more annotations |
Human Phenotypes | Abnormal retinal vascular morphology |
Attenuation of retinal blood vessels |
Keratoconus |
Posterior subcapsular cataract |
Chorioretinal atrophy |
Optic atrophy |
Optic disc pallor |
Abnormality of retinal pigmentation |
Bone spicule pigmentation of the retina |
Retinal degeneration |
Rod-cone dystrophy |
Abnormal electroretinogram |
Nystagmus |
Ophthalmoplegia |
Nyctalopia |
Progressive night blindness |
Photophobia |
Photopsia |
Visual impairment |
Blindness |
Peripheral visual field loss |
Glaucoma |
Disease(s) Associated with FSCN2 | ||||||||||||||||||||||
retinitis pigmentosa | ||||||||||||||||||||||
retinitis pigmentosa 30 |
Mouse Phenotypes | abnormal photoreceptor inner segment morphology |
photoreceptor inner segment degeneration |
abnormal photoreceptor outer segment morphology |
abnormal photoreceptor outer segment size |
short photoreceptor outer segment |
photoreceptor outer segment degeneration |
abnormal retina morphology |
thin retina inner nuclear layer |
thin retina outer nuclear layer |
retina outer nuclear layer degeneration |
increased susceptibility to age-related retinal degeneration |
decreased total retina thickness |
retina degeneration |
decreased a-wave amplitude |
decreased b-wave amplitude |
abnormal eye electrophysiology |
abnormal cone electrophysiology |
abnormal rod electrophysiology |
abnormal vision |
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Availability | Mouse Genotype | |||||||||||||||||||
Fscn2em1Fhan/Fscn2em1Fhan | ||||||||||||||||||||
Fscn2tm1Sykk/Fscn2tm1Sykk | ||||||||||||||||||||
Fscn2tm2Sykk/Fscn2tm2Sykk | ||||||||||||||||||||
Fscn2tm1Sykk/Fscn2+ | ||||||||||||||||||||
Fscn2tm2Sykk/Fscn2+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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