Symbol Name ID |
Rb1
RB transcriptional corepressor 1 MGI:97874 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Vitreous hemorrhage |
Leukocoria |
Retinoblastoma |
Retinal calcification |
Vitritis |
Disease(s) Associated with RB1 | |||||
osteosarcoma | |||||
retinoblastoma |
Mouse Phenotypes | vision/eye phenotype |
increased lens fiber apoptosis |
abnormal retina apoptosis |
decreased retina apoptosis |
increased retina apoptosis |
decreased retina ganglion cell number |
decreased retina photoreceptor cell number |
decreased retina rod cell number |
absent retina bipolar cells |
abnormal retina horizontal cell morphology |
abnormal lens development |
abnormal lens fiber morphology |
cataract |
abnormal retina morphology |
abnormal retina ganglion layer morphology |
abnormal retina inner nuclear layer morphology |
thin retina inner nuclear layer |
disorganized retina inner nuclear layer |
abnormal retina inner plexiform layer morphology |
thin retina inner plexiform layer |
thin retina outer nuclear layer |
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Availability | Mouse Genotype | |||||||||||||||||||||
Rb1tm1.1Jyjw/Rb1tm1.1Jyjw | ||||||||||||||||||||||
Rb1tm1Brd/Rb1tm1Brd | * | |||||||||||||||||||||
Rb1tm1Dwg/Rb1tm1Dwg | ||||||||||||||||||||||
Rb1tm1Jyjw/Rb1tm1Jyjw | ||||||||||||||||||||||
Rb1tm1Mlh/Rb1tm1Mlh | * | |||||||||||||||||||||
Rb1tm1Tyj/Rb1tm1Tyj | * | |||||||||||||||||||||
Rb1tm1Tyj/Rb1tm1Tyj Tg(Rb1)1Blg/0 |
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Rb1tm2Mlh/Rb1tm2Mlh | * | |||||||||||||||||||||
Rb1tm1.1Jyjw/Rb1+ | ||||||||||||||||||||||
Rb1tm1Jyjw/Rb1+ | ||||||||||||||||||||||
Rb1tm1Tyj/Rb1tm2Tyj | * | |||||||||||||||||||||
Rb1tm2Brn/Rb1tm2Brn Tg(Rbp3-cre)1Brn/0 (conditional) |
* | |||||||||||||||||||||
Rb1tm3Tyj/Rb1tm3Tyj Tg(Pax6-cre,GFP)2Pgr/0 (conditional) |
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Rb1tm3Tyj/Rb1tm3Tyj Tg(Nes-cre)1Atp/0 (conditional) |
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Rb1tm1Dwg/Rb1tm2Brn Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 (conditional) |
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Rb1tm3Tyj/Rb1tm3.1Tyj Tg(Nes-cre)1Atp/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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