Symbol Name ID |
Sod2
superoxide dismutase 2, mitochondrial MGI:98352 |
Darker colors indicate more annotations |
Human Phenotypes | Retinal hemorrhage |
Central retinal vessel vascular tortuosity |
Choroidal neovascularization |
Optic atrophy |
Optic disc drusen |
Leber optic atrophy |
Optic neuropathy |
Macular degeneration |
Angioid streaks of the fundus |
Retinal peau d'orange |
Retinopathy |
Blue sclerae |
Myopia |
Metamorphopsia |
Visual impairment |
Reduced visual acuity |
Centrocecal scotoma |
Visual loss |
Progressive visual loss |
Open angle glaucoma |
Disease(s) Associated with SOD2 | ||||||||||||||||||||
Leber hereditary optic neuropathy | ||||||||||||||||||||
neuronal ceroid lipofuscinosis | ||||||||||||||||||||
primary open angle glaucoma | ||||||||||||||||||||
pseudoxanthoma elasticum | ||||||||||||||||||||
systemic lupus erythematosus |
Mouse Phenotypes | abnormal retina vasculature morphology |
retina hemorrhage |
short photoreceptor inner segment |
short photoreceptor outer segment |
abnormal retina rod cell outer segment morphology |
retina photoreceptor degeneration |
abnormal optic nerve morphology |
abnormal retina pigment epithelium morphology |
abnormal retina pigmentation |
retina pigment epithelium atrophy |
abnormal ocular fundus morphology |
abnormal retina morphology |
thin retina inner nuclear layer |
thin retina outer nuclear layer |
abnormal retina photoreceptor layer morphology |
retina degeneration |
abnormal optic choroid morphology |
abnormal Bruch membrane morphology |
decreased a-wave amplitude |
decreased b-wave amplitude |
abnormal cone electrophysiology |
abnormal rod electrophysiology |
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Availability | Mouse Genotype | ||||||||||||||||||||||
Sod2tm1Cje/Sod2tm1Cje | |||||||||||||||||||||||
Sod2tm1Kskk/Sod2tm1Kskk Tg(BEST1-rtTA,tetO-cre)1Yzl/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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