Compare GO annotations for GLA and its Reference Genomes orthologs

Compare GO annotations for GLA and its orthologs

Possible outliers might be spotted in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, zfish, fly, worm, dicty, dicot, yeast, pombe, ecoli.
Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Red arrows indicate "regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Zfish from Zfin; Fly from Flybase; Worm from Wormbase; Dicot from TAIR; Dicty from Dictybase; Yeast from SGD; Pombe from Sanger; Ecoli from EcoliHub.
Organisms with experimental annotations are indicated: IC, IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Thu Jan 8 13:33:51 2009.

Compare annotations to GO categories for GLA.

Entry indicates that ortholog exists for this gene.
Colored entries indicate experimental annotation.
Parentheses indicate ISS annotation only.

Category	ID	Term	Human	Mouse	Rat	Chicken	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	Ecoli
Molecular Function	GO:0005488	binding	Human	Mouse	Rat	X	Zfish	X	Worm	Dicty	Dicot	X	X	X
Molecular Function	GO:0003824	catalytic activity	Human	Mouse	Rat	X	Zfish	X	Worm	(Dicty)	Dicot	X	X	X
Cellular Component	GO:0005623	cell	Human	Mouse	Rat	X	Zfish	X	Worm	Dicty	Dicot	X	X	X
Cellular Component	GO:0044464	cell part	Human	Mouse	Rat	X	Zfish	X	Worm	Dicty	Dicot	X	X	X
Cellular Component	GO:0005576	extracellular region	Human	Mouse	(Rat)	X	Zfish	X	Worm	Dicty	Dicot	X	X	X
Cellular Component	GO:0043226	organelle	Human	Mouse	Rat	X	Zfish	X	Worm	Dicty	Dicot	X	X	X
Biological Process	GO:0065007	biological regulation	(Human)	Mouse	Rat	X	Zfish	X	Worm	Dicty	Dicot	X	X	X
Biological Process	GO:0009987	cellular process	(Human)	Mouse	(Rat)	X	Zfish	X	Worm	Dicty	Dicot	X	X	X
Biological Process	GO:0008152	metabolic process	Human	Mouse	(Rat)	X	Zfish	X	Worm	(Dicty)	Dicot	X	X	X
Biological Process	GO:0048519	negative regulation of biological process	(Human)	Mouse	Rat	X	Zfish	X	Worm	Dicty	Dicot	X	X	X
Biological Process	GO:0050789	regulation of biological process	(Human)	Mouse	Rat	X	Zfish	X	Worm	Dicty	Dicot	X	X	X

Full set of experimental (and ISS) annotations for GLA

Category	ID	Term	DB Object	Evidence	With_From	Organism	Reference
Molecular Function	GO:0004557	alpha-galactosidase activity	GLA	IMP		Human	PMID:16372133
Molecular Function	GO:0004557	alpha-galactosidase activity	GLA	IDA		Human	PMID:39940
Molecular Function	GO:0004557	alpha-galactosidase activity	Gla	IDA		Mouse	MGI:MGI:54349\|PMID:198184
Molecular Function	GO:0004557	alpha-galactosidase activity	Gla	IDA		Mouse	MGI:MGI:54860\|PMID:6251472
Molecular Function	GO:0004557	alpha-galactosidase activity	Gla	IDA		Mouse	MGI:MGI:55533\|PMID:6852525
Molecular Function	GO:0004557	alpha-galactosidase activity	Gla	IDA		Mouse	MGI:MGI:57368\|PMID:2890215
Molecular Function	GO:0004557	alpha-galactosidase activity	Gla	IDA		Mouse	MGI:MGI:58084\|PMID:2906327
Molecular Function	GO:0004557	alpha-galactosidase activity	Gla	IDA		Mouse	MGI:MGI:54440\|PMID:205481
Molecular Function	GO:0004557	alpha-galactosidase activity	Gla	IDA		Mouse	MGI:MGI:54345\|PMID:895843
Molecular Function	GO:0004557	alpha-galactosidase activity	Gla	IMP	MGI:MGI:1861794	Mouse	MGI:MGI:86774\|PMID:9122231
Molecular Function	GO:0004557	alpha-galactosidase activity	Gla	IDA		Mouse	MGI:MGI:54232\|PMID:1008807
Molecular Function	GO:0004557	alpha-galactosidase activity	Gla	IDA		Mouse	MGI:MGI:3525994\|PMID:15629890
Molecular Function	GO:0004557	alpha-galactosidase activity	Gla	IDA		Mouse	MGI:MGI:1929362\|PMID:11115376
Molecular Function	GO:0004557	alpha-galactosidase activity	Gla	IDA		Mouse	MGI:MGI:1860035\|PMID:10840053
Molecular Function	GO:0004557	alpha-galactosidase activity	Gla	ISS	RGD:10650	Rat	RGD:1624291
Molecular Function	GO:0004557	alpha-galactosidase activity	Gla	IDA		Rat	RGD:1625498\|PMID:8702598
Molecular Function	GO:0004557	alpha-galactosidase activity	Gla	IMP		Rat	RGD:1625507\|PMID:8717430
Molecular Function	GO:0004557	alpha-galactosidase activity	Gla	ISS	RGD:1344140	Rat	RGD:1624291
Molecular Function	GO:0016936	galactoside binding	Gla	IDA		Rat	RGD:1625498\|PMID:8702598
Molecular Function	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	DDB_G0291524	ISS	InterPro:IPR002241	Dicty	dictyBase_REF:10155
Molecular Function	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	melA	ISS	InterPro:IPR002241	Dicty	dictyBase_REF:10155
Molecular Function	GO:0042803	protein homodimerization activity	GLA	IDA		Human	PMID:6256390
Molecular Function	GO:0042803	protein homodimerization activity	Gla	ISS	RGD:1344140	Rat	RGD:1624291
Molecular Function	GO:0005102	receptor binding	GLA	IDA		Human	PMID:1332979
Molecular Function	GO:0005102	receptor binding	Gla	ISS	RGD:1344140	Rat	RGD:1624291
Cellular Component	GO:0048046	apoplast	AtAGAL1	IDA		Dicot	TAIR:Publication:501725189\|PMID:18538804
Cellular Component	GO:0005618	cell wall	AtAGAL1	IDA		Dicot	TAIR:Publication:501714811\|PMID:15593128
Cellular Component	GO:0005737	cytoplasm	GLA	IMP		Human	PMID:1332979
Cellular Component	GO:0005737	cytoplasm	Gla	ISS	RGD:1344140	Rat	RGD:1624291
Cellular Component	GO:0005737	cytoplasm	GANA-1	IDA		Worm	WB:WBPaper00024995
Cellular Component	GO:0005576	extracellular region	GLA	IMP		Human	PMID:1332979
Cellular Component	GO:0005576	extracellular region	GLA	IDA		Human	PMID:3029062
Cellular Component	GO:0005576	extracellular region	Gla	ISS	RGD:1344140	Rat	RGD:1624291
Cellular Component	GO:0005794	Golgi apparatus	GLA	IMP		Human	PMID:1332979
Cellular Component	GO:0005794	Golgi apparatus	Gla	ISS	RGD:1344140	Rat	RGD:1624291
Cellular Component	GO:0005764	lysosome	GLA	IMP		Human	PMID:1332979
Cellular Component	GO:0005764	lysosome	Gla	IDA		Mouse	MGI:MGI:3525994\|PMID:15629890
Cellular Component	GO:0005764	lysosome	Gla	ISS	RGD:10650	Rat	RGD:1624291
Cellular Component	GO:0005764	lysosome	Gla	IDA		Rat	RGD:1625498\|PMID:8702598
Cellular Component	GO:0005764	lysosome	Gla	ISS	RGD:1344140	Rat	RGD:1624291
Cellular Component	GO:0005625	soluble fraction	Gla	IDA		Rat	RGD:1625498\|PMID:8702598
Cellular Component	GO:0005773	vacuole	AT3G56310.1	IDA		Dicot	TAIR:Publication:501712581\|PMID:15215502
Cellular Component	GO:0005773	vacuole	AT3G56310.1	IDA		Dicot	TAIR:Publication:501714874\|PMID:15539469
Cellular Component	GO:0005773	vacuole	AT3G56310.2	IDA		Dicot	TAIR:Publication:501714874\|PMID:15539469
Biological Process	GO:0005975	carbohydrate metabolic process	DDB_G0291524	ISS	InterPro:IPR002241	Dicty	dictyBase_REF:10155
Biological Process	GO:0005975	carbohydrate metabolic process	melA	ISS	InterPro:IPR002241	Dicty	dictyBase_REF:10155
Biological Process	GO:0016139	glycoside catabolic process	gana-1	IMP		Worm	WB:WBPaper00024995
Biological Process	GO:0046477	glycosylceramide catabolic process	Gla	IMP	MGI:MGI:1861794	Mouse	MGI:MGI:86774\|PMID:9122231
Biological Process	GO:0046477	glycosylceramide catabolic process	Gla	IMP	MGI:MGI:1861794	Mouse	MGI:MGI:1859538\|PMID:10841515
Biological Process	GO:0046477	glycosylceramide catabolic process	Gla	IDA		Mouse	MGI:MGI:1860035\|PMID:10840053
Biological Process	GO:0046477	glycosylceramide catabolic process	Gla	IDA		Mouse	MGI:MGI:3525994\|PMID:15629890
Biological Process	GO:0046477	glycosylceramide catabolic process	Gla	IMP	MGI:MGI:1861794	Mouse	MGI:MGI:2155538\|PMID:11752062
Biological Process	GO:0046477	glycosylceramide catabolic process	Gla	ISS	RGD:10650	Rat	RGD:1624291
Biological Process	GO:0045019	negative regulation of nitric oxide biosynthetic process	GLA	ISS	UniProtKB:P51569	Human	UniProtKB:P06280
Biological Process	GO:0051001	negative regulation of nitric-oxide synthase activity	GLA	ISS	UniProtKB:P51569	Human	UniProtKB:P06280
Biological Process	GO:0009311	oligosaccharide metabolic process	GLA	IDA		Human	PMID:39940
Biological Process	GO:0009311	oligosaccharide metabolic process	Gla	ISS	RGD:1344140	Rat	RGD:1624291

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)