This mutation was derived from the parent line <a href="http://www.informatics.jax.org/accession/MGI:5311366">b2b370Clo</a>.  <br><br>
<b>Summative Diagnosis:</b> 
<br> Cardiovascular defects: Right aortic arch (RAA), hypoplastic ascending aorta and brachiocephalic arteries. <br>Non-cardiac defects: Noncardiac defects: Craniofacial defects - proboscis, micrognathia, no oral cavity opening (no mouth), holosproencephaly  

<br><br><b>Fyler Codes</b>
<br>The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (<A HREF="http://www.ipccc.net/">http://www.ipccc.net/</A>).
<table>
<br><br>
<table border="1">
  <tr> 
    <th>Fyler Code ID</th> 
    <th>Code Description</th> 
  </tr>
<tr> 
    <td>2600</td> 
    <td>Systemic artery anomaly</td> 
  </tr>
<tr> 
    <td>2700</td> 
    <td>Abnormal aortic arch</td> 
  </tr>
<tr> 
    <td>2721</td> 
    <td>Right aortic arch with abnormal branching pattern</td> 
  </tr>

<tr> 
    <td>3804</td> 
    <td>Congenital heart disease</td> 
  </tr>

<tr> 
    <td>4163</td> 
    <td>Micrognathia</td> 
  </tr>
<tr> 
    <td>4874</td> 
    <td>Mouth malformation</td> 
  </tr>
<tr> 
    <td>4907</td> 
    <td>Non-cardiac thoracic abnormality</td> 
  </tr> 
</table><br>