This mutation was derived from the parent line <a href="http://www.informatics.jax.org/accession/MGI:5313714">b2b508Clo</a>. <br><br>
<b>Summative Diagnosis:</b>
<br> Mutant Phenotype I: Cardiac defects: DORV, AVSD, VSD. Noncardiac defects: Microcephaly, micrognathia, anopthalmia.     
<br><br><b>Fyler Codes</b>
<br>The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (<A HREF="http://www.ipccc.net/">http://www.ipccc.net/</A>).
<table>
<br><br>
<table border="1">
  <tr> 
    <th>Fyler Code ID</th>
    <th>Code Description</th> 
  </tr> 

<tr> 
    <td>0600</td>
    <td>Double outlet right ventricle</td> 
  </tr> 
<tr> 
    <td>0606</td>
    <td>DORV + AVSD (AV canal)</td> 
  </tr> 
<tr> 
    <td>1100</td>
    <td>Atrioventricular canal (endocardial cushion defect)</td> 
  </tr> 
  

<tr> 
    <td>1300</td>
    <td>Ventricular septal defect</td> 
  </tr>
<tr> 
    <td>4163</td>
    <td>Micrognathia</td> 
  </tr>

<tr> 
    <td>4310</td>
    <td>Microcephaly</td> 
  </tr>

<tr> 
    <td>4864</td>
    <td>Anophthalmia</td> 
  </tr>  

</table><br>