The image shown here is of a two littermate mice where the right is homozygous for
the spontaneous "obese" allele of leptin (
Lepob
/Lepob).
Leptin is a hormone which regulates body fat as well as the sensation of
hunger, and mice with homozygous loss-of-function alleles are hyperphagic,
obese, and susceptible to diabetes and other complications.
Phenotype Images in MGI
Whenever possible the text annotations of phenotypes
in MGI are complemented by images illustrating
the phenotype (photographs, histology, x-rays, etc.).
Images may be found on the relevant allele detail page(s).
Phenotype images come either from journal articles
(with permission of the journal) or through contributed submissions.
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Phenotype Images
