Glossary:Loss-of-function Mutation

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Glossary Term

Glossary Term	Loss-of-function Mutation MGI Glossary
Definition	A type of mutation in which the altered gene product lacks the molecular function of the wild-type gene. Synonyms: Amorphic Mutation, Null Mutation. See also: Antimorphic Mutation Gain-of-function Mutation Hypermorphic Mutation Hypomorphic Mutation Neomorphic Mutation

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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