Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; HMG box domain binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including BMP signaling pathway; endochondral ossification; and osteoblast differentiation. Acts upstream of or within several processes, including embryonic morphogenesis; neuron differentiation; and regulation of gene expression. Located in chromatin; cytoplasm; and nucleus. Is expressed in several structures, including alimentary system; embryo ectoderm; embryo mesenchyme; nervous system; and sensory organ. Used to study split hand-foot malformation 1. Human ortholog(s) of this gene implicated in split hand-foot malformation 1 and split hand-foot malformation 1 with sensorineural hearing loss. Orthologous to human DLX5 (distal-less homeobox 5).

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Gene Ontology Evidence Code Abbreviations:

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