Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in cartilage development; negative regulation of transcription by RNA polymerase II; and positive regulation of gene expression. Acts upstream of or within several processes, including calcineurin-NFAT signaling cascade; lncRNA transcription; and positive regulation of myoblast fusion. Located in chromatin; cytosol; and nucleus. Part of ribonucleoprotein complex and transcription regulator complex. Is expressed in several structures, including central nervous system; genitourinary system; jaw; lung; and thymus primordium. Orthologous to human NFATC2 (nuclear factor of activated T cells 2).
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