Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.5.0)

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including lymphoid lineage cell migration into thymus; regulation of positive thymic T cell selection; and thymus epithelium morphogenesis. Acts upstream of or within several processes, including nail development; regulation of T cell differentiation in thymus; and thymus development. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; foregut; integumental system; male reproductive gland or organ; and thymus. Used to study DiGeorge syndrome and T-cell immunodeficiency, congenital alopecia, and nail dystrophy. Human ortholog(s) of this gene implicated in T-cell immunodeficiency, congenital alopecia, and nail dystrophy; alopecia; nail disease; and primary immunodeficiency disease. Orthologous to human FOXN1 (forkhead box N1).

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Gene Ontology Evidence Code Abbreviations:

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