Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; nucleic acid binding activity; and transcription regulator inhibitor activity. Involved in dendritic transport of messenger ribonucleoprotein complex; negative regulation of DNA-binding transcription factor activity; and negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including epithelial cell proliferation; lymphocyte proliferation; and negative regulation of DNA-templated transcription. Located in cytoplasm; dendrite; and neuronal cell body. Is active in glutamatergic synapse; nucleus; and postsynapse. Is expressed in several structures, including alimentary system; eye; genitourinary system; heart; and nervous system. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 31. Orthologous to human PURA (purine rich element binding protein A).

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Gene Ontology Evidence Code Abbreviations:

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